The Frequency of Discordant Gyrase A Genotypes Among Cases of Multiple Neisseria gonorrhoeae Infections at Different Anatomic Sites.

The Frequency of Discordant Gyrase A Genotypes Among Cases of Multiple Neisseria gonorrhoeae Infections at Different Anatomic Sites.
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不同解剖部位多重淋病奈瑟菌感染病例中旋转酶 A 基因型不一致的频率。

DOI:
10.1097/olq.0000000000000912
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发表时间:
2019
影响因子:
3.1
通讯作者:
Klausner,JeffreyD
Klausner,JeffreyD
中科院分区:
医学4区
文献类型:
--
作者:
Allan-Blitz,Lao-Tzu;Ellis,OliviaL;Bolan,Robert;Hemarajata,Peera;Humphries,RomneyM;Shahkolahi,Akbar;McGrath,Mark;Klausner,JeffreyD

文献摘要

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方法我们对2015年11月1日至2017年4月28日在加州大学洛杉矶分校成功进行基因分型的所有淋病奈瑟菌病例进行了回顾性图表审查。经Cobas 4800CT/NG试验(罗氏分子系统,Pleasanton,CA)检测为淋病奈瑟菌阳性的标本进行gyrA基因分型。单个病例被定义为在给定日期在一个或多个解剖部位新诊断的淋病奈瑟菌感染。
METHODSWe performed a retrospective chart review of all N. gonorrhoeae cases with more than 1 anatomic site of involvement that were successfully genotyped between November 1, 2015, and April 28, 2017, at the University of California Los Angeles. Specimens that were N. gonorrhoeae positive as determined by the Cobas 4800 CT/NG Assay (Roche Molecular Systems, Pleasanton, CA) were reflexed to gyrA genotyping. A single case was defined as a new diagnosis of N. gonorrhoeae infection at one or more anatomic site on a given date.