Low serum testosterone and increased mortality in men with coronary heart disease
Low serum testosterone and increased mortality in men with coronary heart disease
复制标题
DOI：
10.1136/hrt.2010.195412
复制
发表时间：
2010-11-01
期刊：
影响因子：
5.7
通讯作者：
Channer, Kevin S.
中科院分区：
文献类型：
--
作者：
Malkin, Chris J.;Pugh, Peter J.;Channer, Kevin S.
研究背景：研究血清睾酮水平对连续确诊冠心病男性患者生存的影响，并计算睾酮缺乏的患病率。设计纵向随访研究。三级转诊心胸中心。在2000年6月至2002年6月期间招募了930名连续接受冠脉造影诊断的男性患者，随访时间平均为6.9±62.1年。结果：全因死亡率和血管死亡率。睾酮缺乏的普遍性。结果利用生物可利用睾酮（bio-T）测定冠心病人群生化睾酮缺乏症的总体患病率
Background To examine the effect of serum testosterone levels on survival in a consecutive series of men with confirmed coronary disease and calculate the prevalence of testosterone deficiency.Design Longitudinal follow-up study.Setting Tertiary referral cardiothoracic centre.Patients 930 consecutive men with coronary disease referred for diagnostic angiography recruited between June 2000 and June 2002 and followed up for a mean of 6.9+/-62.1 years.Outcome All-cause mortality and vascular mortality. Prevalence of testosterone deficiency.Results The overall prevalence of biochemical testosterone deficiency in the coronary disease cohort using bio-available testosterone (bio-T)