Preemptive renal transplantation in adults

Preemptive renal transplantation in adults
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DOI:
10.1016/j.transproceed.2005.05.039
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发表时间:
2005-07-01
影响因子:
0.9
通讯作者:
Touchard, G
Touchard, G
中科院分区:
医学4区
文献类型:
--
作者:
Abou Ayache, R;Bridoux, F;Touchard, G

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最近的研究清楚地表明,先发制人的肾移植与更好的移植物和患者存活率有关。与传统的移植相比,它提高了生活质量,是一种经济有效的选择。我们报告了我们使用这一概念的经验,并回顾了文献。我们回顾分析了1986年3月至2004年5月在本中心进行的所有成人肾移植:在463例肾移植中,44例为先发制人(9.5%)。平均随访期为45.7+/-6个月,另一组为62.3+/-2.6个月。研究结束时,移植物存活率分别为93.2%和77.1%(P=0.02)。两组患者存活率相似。在先发制人组中,移植物更有可能来自活体供者(P
Recent studies have clearly demonstrated that preemptive renal transplantation is associated with better graft and patient survival. It improves the quality of life and is a cost-effective option compared to conventional transplantation. We report our experience with this concept and review the literature. We retrospectively analyzed all adult kidney transplantations performed in our center between March 1986 and May 2004: among 463 renal transplantations 44 were preemptive (9.5%). Mean follow-up was 45.7 +/- 6 months in preemptive versus 62.3 +/- 2.6 months in the other group. At the end of the study, graft survivals were 93.2% and 77.1%, respectively (P =.02). Patient survival rates were similar in both groups. In the preemptive group, grafts were more likely to come from living donors (P