Actinobacillus pleuropneumoniae: a review of an economically important pathogen.
Actinobacillus pleuropneumoniae: a review of an economically important pathogen.
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DOI：
10.12968/live.2020.25.6.308
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发表时间：
2020-01-01
期刊：
影响因子：
--
通讯作者：
Velazquez, Eduardo
中科院分区：
文献类型：
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作者：
Gale, Christina;Velazquez, Eduardo
胸膜肺炎放线杆菌是引起猪胸膜肺炎的病原之一，是影响养猪生产的重要呼吸道疾病。临床症状根据疾病的严重程度和肺部病变而有所不同，但包括发烧和严重的呼吸道症状，包括咳嗽和呼吸困难。存在许多血清型，其毒力各不相同，并且血清型的毒力也已被证明在国家之间存在差异。重要的是要确定哪些血清型在农场中存在和活跃，并进行血清分析，以确定实施控制措施（如疫苗接种）的正确时间。了解传播途径是至关重要的，包括农场中持续感染并可能传播细菌从而感染其他动物的带菌者动物的作用。因此，与所有传染病一样，良好的内部和外部生物安全标准对于控制农场疾病非常重要。疫苗接种已被证明在受影响的农场中有效地防止爆发，减少临床症状，如果它们发生，对农民来说最重要的是，防止死亡率，饲料转化率和生长的损失。因此，疫苗通常是控制农场胸膜肺炎和减少使用抗菌剂治疗的需要的良好选择。
Actinobacillus pleuropneumoniae is one of the causative agents of porcine pleuropneumonia, which is an economically important respiratory disease of pig production. Clinical signs vary based on the severity of disease and lung lesions present, but include fever and severe respiratory signs including coughing and laboured breathing. Numerous serotypes exist which vary in their virulence, and virulence of serotypes has also been shown to be vary between countries. It is important to establish which serotypes are present and active on a farm as well as carrying out seroprofiling to determine the correct time for implementation of control measures such as vaccination. Understanding of transmission routes is vital, including the role of carrier animals on the farm which are persistently infected and can shed the bacteria, therefore infecting other animals. Therefore, as with all infectious diseases, good standards of internal and external biosecurity are important in controlling the disease on farm. Vaccination has been shown to be effective on affected farms in preventing outbreaks, reducing clinical signs if they occur, and most important to the farmer, preventing losses in mortality, feed conversion ratio and growth. Therefore, vaccines are often a good choice for controlling pleuropneumonia on farm and reducing the need for treatment using antimicrobials.