Assessing cannabis use in adolescents and young adults: What do urine screen and parental report tell you?
Assessing cannabis use in adolescents and young adults: What do urine screen and parental report tell you?
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DOI：
10.1089/cap.2005.15.742
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发表时间：
2005-10-01
影响因子：
1.9
通讯作者：
Swezey, A
中科院分区：
文献类型：
--
作者：
Gignac, M;Wilens, TE;Swezey, A
目的：我们的分析比较了三种方法来检测成年早期最常见的药物滥用，大麻：(1)报告直接结构化访谈；(2)间接父母报告；(3)尿液毒理学筛查。方法：我们检查了207名受试者（36%也符合酒精滥用标准；9%为酒精依赖标准）的数据，这些数据来自两项前瞻性和正在进行的家庭研究，涉及有或没有注意力缺陷/多动障碍（ADHD）的男孩和女孩。评估依赖于情感障碍和精神分裂症附表（k - ssad - e； 18岁以下）和DSM-IV的结构化临床访谈（SCID-IV； 18岁以上）。尿样采用Auccusign DOA5（现场筛选法）分析。结果：97%的人在过去一个月内没有使用大麻，尿液筛查呈阴性，79%的人承认大麻滥用/依赖，尿液筛查呈阳性。直接结构化访谈报告敏感性91%，特异性87%，阳性预测值67%，阴性预测值97%。与直接报告相比，间接父母报告在大麻使用方面提供的信息较少。结论：与尿液毒理学筛查和间接父母报告相比，在结构化访谈中直接报告大麻使用、滥用或依赖既敏感又具体。
Objectives: Our analysis compares three approaches to detect the most common drug abused in early adulthood, cannabis: (1) report on direct structured interview; (2) indirect parental report; and (3) urine toxicology screen.Methods: We examined data on 207 subjects (36% also met criteria for alcohol abuse; 9% for alcohol dependence) derived from two prospective and ongoing family studies of boys and girls with or without attention-deficit/hyperactivity disorder (ADHD). Assessments relied on the Schedule for Affective Disorders and Schizophrenia (K-SADS-E; under 18 years of age) and on the Structured Clinical Interview for DSM-IV (SCID-IV; over 18 years of age). Urine samples were analyzed with Auccusign DOA5 (on-site screening assay).Results: Ninety-seven percent (97%) of individuals, who reported no use of cannabis within the past month, had a negative urine screening and 79% of individuals, who endorsed cannabis abuse/dependence, had a positive urine screening. The sensitivity of the direct structured interview report was 91%, the specificity 87%, the positive predicting value 67%, and the negative predictive value 97%. Indirect parental reports were found to be less informative on cannabis use than direct report.Conclusion: Direct report of cannabis use, abuse, or dependence during the structured interview is both sensitive and specific when compared to urine toxicology screens and indirect parental reports.