Cross-infection in Infantile Gastroenteritis
Cross-infection in Infantile Gastroenteritis
复制标题
小儿胃肠炎交叉感染
DOI：
10.1136/adc.46.250.815
复制
发表时间：
1971
影响因子：
5.2
通讯作者：
B. Heyworth
中科院分区：
文献类型：
--
作者：
A. Ironside;J. Brennand;B. Mandal;B. Heyworth
即使在设计良好的病房中，有经验的工作人员也不完全可能通过使用传统的屏障护理技术来预防婴儿胃肠炎的医院交叉感染。一起由肠病性埃施引起的双重交叉感染事件。本文介绍了O119和O126型大肠杆菌的流行情况及控制措施。O119型感染在临床上是严重的，病例显示出对该生物体的血清抗体的显著水平，而O126型感染在临床上是轻微的，没有抗体产生。抗生素粘菌素的使用，这两种生物体最初都是敏感的，可能在清除O119型感染方面有一定的价值，但对O126型感染没有影响，O126型感染在治疗期间继续传播。在治疗后分离的O126型微生物的一些菌株中发现了一定程度的粘菌素耐药性。这些疾病的爆发大部分是自发结束的，但可能由于所述的行政措施而在程度上受到限制。使用抗生素在婴儿胃肠炎进行审查，并呼吁现代大规模的试验，以重新评估其价值。
It is not entirely possible to prevent hospital cross-infection in infantile gastroenteritis by the use of conventional barrier-nursing techniques, even with experienced staff in well-designed wards. An incident of double cross-infection due to enteropathic Esch. coli types O119 and O126 and the measures that were taken to control it are described. The type O119 infections were clinically severe, and the cases showed significant levels of serum antibody to the organism, while the type O126 infections were clinically mild and no antibody was produced. The use of the antibiotic colistin, to which both organisms were originally sensitive, may have been of some value in clearing the type O119 infection but was without effect on the type O126 infection, which continued to spread during treatment. A degree of resistance to colistin was found in some strains of the type O126 organism isolated after treatment. The outbreaks largely ended spontaneously, but may have been limited in extent by the administrative measures described. The use of antibiotics in infantile gastroenteritis is reviewed and a plea is made for a modern large-scale trial to reassess their value.