Tissue characterization of skin ulcer for bacterial infection by multiple statistical analysis of echo amplitude envelope
Tissue characterization of skin ulcer for bacterial infection by multiple statistical analysis of echo amplitude envelope
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通过回波幅度包络的多重统计分析来表征细菌感染的皮肤溃疡的组织特征
DOI：
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发表时间：
2016
期刊：
影响因子：
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通讯作者：
Tadashi Yamaguchi
中科院分区：
文献类型：
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作者：
M. Omura;Kenji Yoshida;M. Kohta;Takabumi Kubo;T. Ishiguro;Kazuto Kobayashi;N. Hozumi;Tadashi Yamaguchi
为了表征细菌感染的皮肤溃疡，通过基于Weibull分布和广义伽马分布的回波幅度包络的多重统计分析以及回波幅度包络的平均值与标准差的比率来估计定量超声（QUS）参数。测量对象为三种大鼠模型（非感染、临界定植和感染模型）。超声数据采集使用一个修改后的超声诊断系统的中心频率为11 MHz。同时观察组织病理学图像和二维声速图。它是可能的，以检测典型的组织特征，如感染，通过专注于QUS参数的关系，并指出与散射体结构相一致的特征差异。此外，在每个大鼠模型中，将未感染和感染组织的组织病理学特征和SoS与QUS参数的特征相匹配。
To characterize skin ulcers for bacterial infection, quantitative ultrasound (QUS) parameters were estimated by the multiple statistical analysis of the echo amplitude envelope based on both Weibull and generalized gamma distributions and the ratio of mean to standard deviation of the echo amplitude envelope. Measurement objects were three rat models (noninfection, critical colonization, and infection models). Ultrasound data were acquired using a modified ultrasonic diagnosis system with a center frequency of 11 MHz. In parallel, histopathological images and two-dimensional map of speed of sound (SoS) were observed. It was possible to detect typical tissue characteristics such as infection by focusing on the relationship of QUS parameters and to indicate the characteristic differences that were consistent with the scatterer structure. Additionally, the histopathological characteristics and SoS of noninfected and infected tissues were matched to the characteristics of QUS parameters in each rat model.
DOI：
10.1121/1.419738
发表时间：
1997-07
期刊：
The Journal of the Acoustical Society of America
影响因子：
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作者：
K. Wear;Robert F. Wagner;David G. Brown;Michael F. Insana
通讯作者：
K. Wear;Robert F. Wagner;David G. Brown;Michael F. Insana