Grain feeding and the dissemination of acid-resistant Escherichia coli from cattle

Grain feeding and the dissemination of acid-resistant Escherichia coli from cattle
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DOI:
10.1126/science.281.5383.1666
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发表时间:
1998-09-11
期刊:
影响因子:
56.9
通讯作者:
Russell, JB
Russell, JB
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Diez-Gonzalez, F;Callaway, TR;Russell, JB

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人类的胃是食源性病原体的屏障,但大肠杆菌如果在弱酸性条件下生长,可以在pH 2.0下存活。牛是致病性大肠杆菌的天然宿主。大肠杆菌,和牛饲料主要是粮食有较低的结肠pH值和更耐酸E。比只喂干草的牛要多。根据数量和酸休克后的存活率,饲喂谷物的牛的耐酸E。大肠杆菌的耐酸性比饲喂干草的牛高,但短期饲喂干草大大降低了耐酸性。
The gastric stomach of humans is a barrier to food-borne pathogens, but Escherichia coli can survive at pH 2.0 if it is grown under mildly acidic conditions. Cattle are a natural reservoir for pathogenic E. coli, and cattle fed mostly grain had Lower colonic pH and more acid-resistant E. coli than cattle fed only hay. On the basis of numbers and survival after acid shock, cattle that were fed grain had 10(6)-fold more acid-resistant E. coli than cattle fed hay, but a brief period of hay feeding decreased the acid-resistant count substantially.