Designed graphene-peptide nanocomposites for biosensor applications: A review
Designed graphene-peptide nanocomposites for biosensor applications: A review
复制标题
设计用于生物传感器应用的石墨烯-肽纳米复合材料：综述
DOI：
10.1016/j.aca.2017.06.054
复制
发表时间：
2017
影响因子：
6.2
通讯作者：
魏刚
中科院分区：
文献类型：
--
作者：
王丽;张玉杰;吴爱国;魏刚
利用DNA、蛋白质、肽等生物大分子对石墨烯进行修饰，拓展了石墨烯材料在各个领域的潜在应用。结合的生物大分子可以改善石墨烯基纳米复合材料的生物相容性和生物识别能力，从而大大提高其选择性和灵敏度的生物传感性能。本文就石墨烯-肽纳米复合材料的合成及其在生物传感器中的应用作一综述。石墨烯的生物功能化与专门设计的肽，和石墨烯-肽（单体，纳米纤维，和纳米管）纳米复合材料的合成策略进行了演示。另一方面，进一步介绍了石墨烯肽纳米复合材料生物传感器结构的制备，用于电化学、荧光、电子和光谱生物传感。本文综述了近年来石墨烯-肽基生物传感器的制备和应用研究进展，为石墨烯-肽基生物传感器在生物医学检测和环境分析领域的应用提供参考。
The modification of graphene with biomacromolecules like DNA, protein, peptide, and others extends the.potential applications of graphene materials in various fields. The bound biomacromolecules could.improve the biocompatibility and bio-recognition ability of graphene-based nanocomposites, therefore.could greatly enhance their biosensing performances on both selectivity and sensitivity. In this review,.we presented a comprehensive introduction and discussion on recent advance in the synthesis and.biosensor applications of graphene-peptide nanocomposites. The biofunctionalization of graphene with.specifically designed peptides, and the synthesis strategies of graphene-peptide (monomer, nanofibrils,.and nanotubes) nanocomposites were demonstrated. On the other hand, the fabrication of graphenepeptide.nanocomposite based biosensor architectures for electrochemical, fluorescent, electronic, and.spectroscopic biosensing were further presented. This review includes nearly all the studies on the.fabrication and applications of graphene-peptide based biosensors recently, which will promote the.future developments of graphene-based biosensors in biomedical detection and environmental analysis.