Law and order: Assessing and enforcing compliance with ontological modeling principles in the Foundational Model of Anatomy
Law and order: Assessing and enforcing compliance with ontological modeling principles in the Foundational Model of Anatomy
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DOI:
10.1016/j.compbiomed.2005.04.007
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发表时间:
2006-07-01
影响因子:
7.7
通讯作者:
Bodenreider, Olivier
中科院分区:
文献类型:
--
作者:
Zhang, Songmao;Bodenreider, Olivier
The objective of this study is to provide an operational definition of principles with which well-formed ontologies should comply. We define 15 such principles, related to classification (e.g., no hierarchical cycles are allowed; concepts have a reasonable number of children), incompatible relationships (e.g., two concepts cannot stand both in a taxonomic and partitive relation), dependence among concepts, and the co-dependence of equivalent sets of relations. Implicit relations-embedded in concept names or inferred from a combination of explicit relations-are used in this process in addition to the relations explicitly represented. As a case study, we investigate the degree to which the Foundational Model of Anatomy (FMA)-a large ontology of anatomy-complies with these 15 principles. The FMA succeeds in complying with all the principles: totally with one and mostly with the others. Reasons for non-compliance are analyzed and suggestions are made for implementing effective enforcement mechanisms in ontology development environments. The limitations of this study are also discussed. Published by Elsevier Ltd.