Patterns of Adolescent Depression to Age 20: The Role of Maternal Depression and Youth Interpersonal Dysfunction
Patterns of Adolescent Depression to Age 20: The Role of Maternal Depression and Youth Interpersonal Dysfunction
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DOI：
10.1007/s10802-008-9241-9
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发表时间：
2008-11-01
影响因子：
3.6
通讯作者：
Keenan-Miller, Danielle
中科院分区：
文献类型：
--
作者：
Hammen, Constance;Brennan, Patricia A.;Keenan-Miller, Danielle
相当多的研究集中在青年抑郁症，但需要进一步的信息来描述青春期发病和复发的不同模式。在20岁时定义了四个结果组（早发复发，早发停止，晚发，从未抑郁），并比较了三个预测青年抑郁症的变量：性别，母亲抑郁症和人际功能。此外，有人假设，母亲抑郁症和15至20岁之间的青年抑郁症之间的关联是由早发性抑郁症和15岁时的人际功能障碍介导的。在15岁时对816名社区青年进行了访谈，这些青年根据母亲抑郁症的历史（或不存在）被选为抑郁症风险，其中699人被纳入5年随访。控制性别、早发和人际功能障碍介导了母亲抑郁症和青少年晚期抑郁症之间的联系。观察到男性和女性的不同模式。对于男性产妇抑郁症的影响是由早发性，但不是人际关系的困难，而女性产妇抑郁症的影响是由人际关系的困难，但不是早发性介导。母亲抑郁症不能预测15岁以后抑郁症的首次发作。研究结果表明，需要针对孕产妇抑郁症的性别特异性影响的影响，对青年早期的结果，也突出了不同的模式，青年抑郁症和他们可能对未来的抑郁症的影响。
Considerable research has focused on youth depression, but further information is needed to characterize different patterns of onset and recurrence during adolescence. Four outcome groups by age 20 were defined (early onset-recurrent, early-onset-desisting, later-onset, never depressed) and compared on three variables predictive of youth depression: gender, maternal depression, and interpersonal functioning. Further, it was hypothesized that the association between maternal depression and youth depression between 15 and 20 is mediated by early-onset depression and interpersonal dysfunction by age 15. Eight hundred sixteen community youth selected for depression risk by history (or absence) of maternal depression were interviewed at age 15, and 699 were included in the 5-year follow-up. Controlling for gender, early onset and interpersonal dysfunction mediated the link between maternal depression and late adolescent major depression. Different patterns for males and females were observed. For males maternal depression's effect was mediated by early onset but not interpersonal difficulties, while for females maternal depression's effect was mediated by interpersonal difficulties but not early onset. Maternal depression did not predict first onset of major depression after age 15. The results suggest the need for targeting the impact of maternal depression's gender-specific effects on early youth outcomes, and also highlight the different patterns of major depression in youth and their likely implications for future course of depression.