Progress of research on antiferroptosis and antipyroptosis effects of gastrodin
Progress of research on antiferroptosis and antipyroptosis effects of gastrodin
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DOI：
10.1002/ibra.12118
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发表时间：
2023-07
期刊：
影响因子：
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通讯作者：
Xue Zheng;Jing Li;Zhao‐Qiong Zhu
中科院分区：
文献类型：
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作者：
Xue Zheng;Jing Li;Zhao‐Qiong Zhu
Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory, antioxidant, antiapoptosis, and other aspects. As the global aging process continues to intensify, diseases of the central nervous system, cardiovascular system, and immune system have brought serious economic and mental burdens to families and have become a major challenge for global public health resources. Many studies have proved that gastrodin may be a potential drug for neurological diseases and ischemic injury but its mechanism of action is still unclear. [Correction added on 19 February 2025, after first online publication: In the preceding sentence, “the treatment of various systemic diseases” has been corrected to “neurological diseases and ischemic injury” in this version.]. In this study, the pharmacological action of gastrodin and the possible mechanism of regulating ferroptosis and pyroptosis were reviewed to provide a new treatment and research direction for clinicians and researchers.
