Out of Water: The Origin and Early Diversification of Plant R-Genes
Out of Water: The Origin and Early Diversification of Plant R-Genes
复制标题
离开水：植物 R 基因的起源和早期多样化
DOI：
10.1104/pp.18.00185
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发表时间：
2018-05-01
期刊：
影响因子：
7.4
通讯作者：
Han, Guan-Zhu
中科院分区：
文献类型：
--
作者：
Gao, Yuxia;Wang, Wenqiang;Han, Guan-Zhu
During plant-pathogen interactions, plants use intracellular proteins with nucleotide-binding site and Leu-rich repeat (NBS-LRR) domains to detect pathogens. NBS-LRR proteins represent a major class of plant disease resistance genes (R-genes). Whereas R-genes have been well characterized in angiosperms, little is known about their origin and early diversification. Here, we perform comprehensive evolutionary analyses of R-genes in plants and report the identification of R-genes in basal-branching streptophytes, including charophytes, liverworts, and mosses. Phylogenetic analyses suggest that plant R-genes originated in charophytes and R-proteins diversified into TIR-NBS-LRR proteins and non-TIR-NBS-LRR proteins in charophytes. Moreover, we show that plant R-proteins evolved in a modular fashion through frequent gain or loss of protein domains. Most of the R-genes in basal-branching streptophytes underwent adaptive evolution, indicating an ancient involvement of R-genes in plant-pathogen interactions. Our findings provide novel insights into the origin and evolution of R-genes and the mechanisms underlying colonization of terrestrial environments by plants.
