Plasmodium falciparum Pfs40, renamed Pf39, is localized to an intracellular membrane-bound compartment and is not sexual stage-specific.
Plasmodium falciparum Pfs40, renamed Pf39, is localized to an intracellular membrane-bound compartment and is not sexual stage-specific.
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恶性疟原虫 Pfs40（更名为 Pf39）定位于细胞内膜结合区室，并且不具有性阶段特异性。
DOI：
10.1016/s0166-6851(97)00164-3
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发表时间：
1997
影响因子：
1.5
通讯作者：
Kaslow,DC
中科院分区：
文献类型：
--
作者：
Templeton,TJ;Fujioka,H;Aikawa,M;Parker,KC;Kaslow,DC
对恶性疟原虫推测的Pfs40基因产物的研究表明，它不在寄生虫细胞表面表达，因此很可能是一种不同于先前描述的有性阶段特异性40 kDa细胞表面蛋白的蛋白质。对克隆的基因进行了鉴定和定义，并将其重命名为Pf39，它是一种在有性和无性阶段都表达的蛋白质。它定位于细胞内的膜室，提示内质网。
Studies of the product of the presumed Pfs40 gene ofPlasmodium falciparumshowed that it is not expressed on the parasite cell surface and is therefore likely to be a protein distinct from the previously described sexual-stage specific 40-kDa cell surface protein. The cloned gene was characterized and defined, and renamed Pf39, as a protein expressed in both sexual and asexual stages. It is localized to an intracellular membranous compartment suggestive of endoplasmic reticulum.