Bothersome urinary symptoms and disease-specific quality of life in patients with benign prostatic obstruction -: High prevalence of urinary incontinence before and after intervention
Bothersome urinary symptoms and disease-specific quality of life in patients with benign prostatic obstruction -: High prevalence of urinary incontinence before and after intervention
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DOI：
10.1080/00365590601068926
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发表时间：
2007-01-01
影响因子：
--
通讯作者：
Spangberg, Anders
中科院分区：
文献类型：
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作者：
Marklund-Bau, Helen;Edell-Gustafsson, Ulla;Spangberg, Anders
目标.首先，描述症状性良性前列腺梗阻（BPO）患者在干预前和干预后6个月自我报告的泌尿系统症状和困扰，包括疾病特异性生活质量（QOL）。第二，确定预测疾病特异性生活质量的因素。第三，开发和测试一个工具，以评估失禁，林雪平失禁问卷（LIQ）的可靠性。最后，翻译和测试瑞典版的国际前列腺症状评分，包括困扰问题，美国泌尿外科协会症状问题指数（SPI）和良性前列腺增生影响指数的可靠性。材料和方法。使用结构化问卷对572/720例连续治疗患者的疾病特异性QOL进行了研究。对122例下尿路症状（LUTS）或BPO患者进行了可靠性测试。结果SPI的频率和弱流项目是最能解释干预前后患者疾病特异性生活质量的项目之一。在干预前后，使用LIQ仪器评估的尿失禁患病率分别为46%和16%。症状和疾病特异性生活质量改善在手术组中最多，在经尿道前列腺切开术/经尿道微波热疗组中居中，在药物治疗组中最少。结论. SPI的频率和弱流项目是最能解释疾病特异性生活质量的因素。干预前后尿失禁的患病率高于以往报道。
Objectives. Firstly, to describe self-reported urinary symptoms and bothersomeness, including disease-specific quality of life (QOL), in patients with symptomatic benign prostatic obstruction (BPO) before and 6 months after intervention. Secondly, to identify factors which predict disease-specific QOL. Thirdly, to develop and test the reliability of an instrument to evaluate incontinence, the Linkoping Incontinence Questionnaire (LIQ). Finally, to translate and test the reliability of Swedish versions of the International Prostate Symptom Score, including the bother question, the American Urological Association Symptom Problem Index (SPI) and the Benign Prostatic Hyperplasia Impact Index. Material and methods. Disease-specific QOL was studied in 572/720 consecutively treated patients using structured questionnaires. The reliability of the instruments was tested in 122 patients with lower urinary tract symptoms (LUTS) or BPO. Results. The frequency and weak stream items of the SPI were among those that best explained the patients' disease-specific QOL both before and after intervention. Before and after intervention the prevalence of urinary incontinence, assessed using the LIQ instrument, was 46% and 16%, respectively. Symptoms and disease-specific QOL improved most in the surgery group, intermediately in the transurethral incision of the prostate/transurethral microwave thermotherapy group and least in the drug therapy group. Conclusions. The frequency and weak stream items of the SPI were the factors that best explained disease-specific QOL. The prevalence of incontinence before and after intervention was higher than that previously reported.