Design, synthesis, and nematicidal activities of novel 1,3-thiazin(thiazol)-4-one derivatives against Meloidogyne incognita
Design, synthesis, and nematicidal activities of novel 1,3-thiazin(thiazol)-4-one derivatives against Meloidogyne incognita
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新型1,3-噻嗪(噻唑)-4-酮衍生物的设计、合成和杀线虫活性
DOI：
10.1177/1747519819857506
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发表时间：
2019-05-01
影响因子：
1.4
通讯作者：
Xu, Xiaoyong
中科院分区：
文献类型：
--
作者：
Jia, Haowu;Guo, Wei;Xu, Xiaoyong
采用Suzuki偶联法合成了4个系列新型1,3-噻嗪（噻唑）-4- 1衍生物。初步生物实验表明，大多数合成的化合物在20 mg L−1浓度下对根结线虫（Meloidogyne spp.）具有良好的体内抑制活性。结果表明，在1 mg L−1浓度下，两种化合物的抑菌活性分别为46.4%和41.4%。
Four series of novel 1,3-thiazin(thiazol)-4-one derivatives were synthesized by Suzuki coupling. Preliminary bioassays showed that most of the synthesized compounds exhibited good inhibitory activity in vivo against root-knot nematodes, Meloidogyne spp. at 20 mg L−1. Among the tested compounds, we found that two compounds displayed 46.4% and 41.4% inhibitory activity even at 1 mg L−1, respectively.