Adrenal and nephrogenic hypertension: an image quality study of low tube voltage, low-concentration contrast media combined with adaptive statistical iterative reconstruction
Adrenal and nephrogenic hypertension: an image quality study of low tube voltage, low-concentration contrast media combined with adaptive statistical iterative reconstruction
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肾上腺和肾性高血压：低管电压、低浓度造影剂结合自适应统计迭代重建的图像质量研究
DOI：
10.1111/ijcp.12860
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发表时间：
2016-09-01
影响因子：
2.6
通讯作者：
Hu, Daoyu
中科院分区：
文献类型：
--
作者：
Li, Zhen;Li, Qiong;Hu, Daoyu
目的本研究旨在探讨采用低管电压、低浓度造影剂和自适应统计迭代重建（ASIR）对肾上腺性和肾性高血压患者减少辐射和碘造影剂剂量的效果。方法和材料将148例疑似肾上腺病变或肾动脉狭窄的高血压患者分为两组。 A组（n=74）接受低管电压、低分子量右旋糖酐增强多排螺旋CT（MDCT）（80kVp，270mgI/mL造影剂），并使用标准滤波反投影（FBP）和ASIR在四种不同混合水平（分别为20%、40%、60%和80%）下重建原始数据。对照组（B组，n=74）接受常规MDCT（120kVp，370mgI/mL造影剂），并用FBP重建数据。测量肾血管、正常肾上腺组织、肾上腺肿瘤和皮下脂肪的CT值、标准差(SD)、信噪比(SNR)和对比噪声比(CNR)。记录体积CT剂量指数（CTDIvol）和剂量长度乘积（DLP），并获得有效剂量（ED）。采用双尾独立t检验、配对卡方检验和Kappa一致性检验对数据进行统计分析。 结果A组CTDIvol、DLP和总碘剂量较B组分别降低47.8%、49.0%和26.07%（P
PurposeThe aim of this study was to investigate the effect of using low tube voltage, low-concentration contrast media and adaptive statistical iterative reconstruction (ASIR) for reducing the radiation and iodine contrast doses in adrenal and nephrogenic hypertension patients.Methods and materialsA total of 148 hypertension patients who were suspected for adrenal lesions or renal artery stenoses were assigned to two groups and. Group A (n=74) underwent a low tube voltage, low molecular weight dextran enhanced multi-detector row spiral CT (MDCT) (80kVp, 270mgI/mL contrast agent), and the raw data were reconstructed with standard filtered back projection (FBP) and ASIR at four different levels of blending (20%, 40%, 60% and 80%, respectively). The control group (Group B, n=74) underwent conventional MDCT (120kVp, 370mgI/mL contrast agent), and the data were reconstructed with FBP. The CT values, standard deviation (SD), signal-noise-ratio (SNR) and contrast-noise-ratio (CNR) were measured in the renal vessels, normal adrenal tissue, adrenal neoplasms and subcutaneous fat. The volume CT dose index (CTDIvol) and dose length product (DLP) were recorded, and an effective dose (ED) was obtained. Two-tailed independent t-tests, paired Chi-square tests and Kappa consistency tests were used for statistical analysis of the data.ResultsThe CTDIvol, DLP and total iodine dose in group A were decreased by 47.8%, 49.0% and 26.07%, respectively, compared to group B (P