Early self-reported post-traumatic stress symptoms after trauma exposure and associations with diagnosis of post-traumatic stress disorder at 3 months: latent profile analysis.
Early self-reported post-traumatic stress symptoms after trauma exposure and associations with diagnosis of post-traumatic stress disorder at 3 months: latent profile analysis.
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DOI：
10.1192/bjo.2023.1
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发表时间：
2023-01-26
期刊：
影响因子：
5.4
通讯作者：
Elhai, Jon D.
中科院分区：
文献类型：
--
作者：
Shih, Chia-Hao;Zhou, Adrian;Grider, Stephen;Xie, Hong;Wang, Xin;Elhai, Jon D.
关键词：
暴露于创伤事件可能引发创伤后应激症状（PTSS），而持续出现PTSS可能会导致创伤后应激障碍（PTSD）的发生。研究表明，创伤发生后数天内出现的PTSS是PTSD发生的一个有力预测指标。
为了探究对创伤的早期应激反应模式及其与PTSD发生的关联，我们从当地一家医院急诊科招募了247名平民创伤幸存者。在创伤事件发生后2周内，这些幸存者完成了《精神疾病诊断与统计手册第五版创伤后应激障碍检查表》（PCL - 5）和急性应激障碍量表（ASDS）。此外，在创伤发生3个月后，其中146名参与者使用《精神疾病诊断与统计手册第五版临床医生-administered PTSD量表》完成了PTSD诊断访谈。
我们首先对PCL - 5的四个症状群以及ASDS的解离症状群进行潜在剖面分析，根据多个拟合指数确定，四剖面模型（“重度症状”“中度症状”“轻度症状”“极轻微症状”）为最优模型。研究发现性别可预测剖面归属。随后我们发现亚组归属与PTSD诊断之间存在显著关联（χ²(3)=11.85，P < 0.01，Cramer's V = 0.263）。事后分析显示，这种关联主要由“重度症状”剖面的参与者驱动，他们发生PTSD的可能性更大。
这些研究结果填补了相关知识空白，即根据创伤后早期PTSS的严重程度确定个体可能存在的亚组，并探究亚组归属与PTSD发生之间的关系，这对临床实践具有重要意义。
Trauma exposure can cause post-traumatic stress symptoms (PTSS), and persistently experiencing PTSS may lead to the development of post-traumatic stress disorder (PTSD). Research has shown that PTSS that emerged within days of trauma was a robust predictor of PTSD development. To investigate patterns of early stress responses to trauma and their associations with development of PTSD. We recruited 247 civilian trauma survivors from a local hospital emergency department. The PTSD Checklist for DSM-5 (PCL-5) and Acute Stress Disorder Scale (ASDS) were completed within 2 weeks after the traumatic event. Additionally, 3 months post-trauma 146 of these participants completed a PTSD diagnostic interview using the Clinician Administered PTSD Scale for DSM-5. We first used latent profile analysis on four symptom clusters of the PCL-5 and the dissociation symptom cluster of the ASDS and determined that a four-profile model (‘severe symptoms’, ‘moderate symptoms’, ‘mild symptoms’, ‘minimal symptoms’) was optimal based on multiple fit indices. Gender was found to be predictive of profile membership. We then found a significant association between subgroup membership and PTSD diagnosis (χ2(3) = 11.85, P < 0.01, Cramer's V = 0.263). Post hoc analysis revealed that this association was driven by participants in the ‘severe symptoms’ profile, who had a greater likelihood of developing PTSD. These findings fill the knowledge gap of identifying possible subgroups of individuals based on their PTSS severity during the early post-trauma period and investigating the relationship between subgroup membership and PTSD development, which have important implications for clinical practice.
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影响因子：
10.3
作者：
Armour, Cherie;Elklit, Ask;Elhai, Jon D.
通讯作者：
Elhai, Jon D.
DOI：
10.1007/978-3-319-26633-6_12
发表时间：
2016-01-01
期刊：
MODERN STATISTICAL METHODS FOR HCI
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