Atrial septostomy in the treatment of severe pulmonary arterial hypertension
Atrial septostomy in the treatment of severe pulmonary arterial hypertension
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DOI：
10.1136/thorax.58.9.797
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发表时间：
2003-09-01
期刊：
影响因子：
10
通讯作者：
Shapiro, LM
中科院分区：
文献类型：
--
作者：
Reichenberger, F;Pepke-Zaba, J;Shapiro, LM
背景资料：方法：对17例重度进行性肺动脉高压患者（原发性肺动脉高压13例，胶原血管病2例，血栓栓塞性疾病1例，血管闭塞性疾病1例）行20例房间隔造口术（AS）。7例患者NYHA III级，10例NYHA IV级。15例患者长期接受前列腺素类药物治疗。结果：AS改善了临床症状，心脏指数从1.8升/分/米2增加到2.2升/分/米2，全身氧转运从263.2 ml/分/米2增加到329.6 ml/分/米2（P
Background: Atrial septostomy (AS) may improve symptoms and haemodynamics in patients with severe pulmonary arterial hypertension (PAH).Methods: Twenty AS performed in 17 patients with severe progressive PAH (13 primary pulmonary hypertension, two collagen vascular disease, one thromboembolic disease, one vaso-occlusive disease) were analysed. Seven patients were in NYHA class III and 10 in NYHA IV. Fifteen patients were on long term prostanoid treatment. AS was performed under fluoroscopy using graded balloon technique.Results: AS improved clinical symptoms and increased the cardiac index from 1.8 to 2.2 l/min/m(2) and systemic oxygen transport from 263.2 to 329.6 ml/min/m(2) (p