When is the Story in the Subgroups?

When is the Story in the Subgroups?
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DOI:
10.1007/s11121-010-0198-x
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发表时间:
2013-04-01
期刊:
影响因子:
3.5
通讯作者:
Michalopoulos, Charles
Michalopoulos, Charles
中科院分区:
医学2区
文献类型:
--
作者:
Bloom, Howard S.;Michalopoulos, Charles

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本文探讨了解释和报告研究样本亚组干预效果估计的策略。本文认为:亚组研究结果为什么以及如何对应用研究很重要,定义亚组的替代方法,激发亚组分析的不同研究问题,在进行分析之前预先指定亚组的重要性,使用现有理论和先前研究来区分研究结果是验证性(假设检验)而不是探索性(假设生成)的亚组的重要性,在何种条件下研究结果应该被认为是确定的。每个问题都通过选定的经验例子加以说明。
This paper examines strategies for interpreting and reporting estimates of intervention effects for subgroups of a study sample. The paper considers: why and how subgroup findings are important for applied research, alternative ways to define subgroups, different research questions that motivate subgroup analyses, the importance of pre-specifying subgroups before analyses are conducted, the importance of using existing theory and prior research to distinguish between subgroups for whom study findings are confirmatory (hypothesis testing) as opposed to exploratory (hypothesis generating), and the conditions under which study findings should be considered confirmatory. Each issue is illustrated by selected empirical examples.