MICROBIOLOGICAL FINDINGS IN PREGNANT-WOMEN WITH PREMATURE RUPTURE OF THE MEMBRANES
MICROBIOLOGICAL FINDINGS IN PREGNANT-WOMEN WITH PREMATURE RUPTURE OF THE MEMBRANES
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DOI：
10.1007/bf02121812
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发表时间：
1980-01-01
影响因子：
5.4
通讯作者：
NORD, CE
中科院分区：
文献类型：
--
作者：
EVALDSON, G;CARLSTROM, G;NORD, CE
本文对30例胎膜早破（PROM）患儿的尿液、宫颈、羊水、胎盘及新生儿鼻咽拭子进行细菌学和病毒学检查。进行病毒血清学调查。胎膜早破组宫颈厌氧菌数多于需氧菌数，对照组需氧菌和厌氧菌总数较少。在胎膜早破患者中，从宫颈、羊水或胎盘中分别分离到23%和30%的脆弱类杆菌和中间链球菌。所有对照品均不含B。fragilis，而S.从6.7%的对照中分离出中间体。20%的胎膜早破患者和6.7%的对照组从母亲宫颈中回收了B族链球菌。4例新生儿败血症，另外2例临床疑似，但未微生物学证实，导致围产儿死亡率高（17.6%）。在胎膜早破的患者中，27%发生了产褥感染，而对照组的母亲没有发生此类并发症。厌氧菌和B组链球菌的意义进行了讨论的情况下，胎膜早破的母亲和新生儿的结果，上行感染在这种并发症的妊娠可能的病因作用被假定。
From 30 consecutive cases of premature rupture of the membranes (PROM) and matched controls, specimens from urine, cervix, amniotic fluid and placenta and neonatal nose and throat swabs were investigated bacteriologically and virologically. Virus serological investigation was done. Among the PROM cases the anaerobic cervical isolates outnumbered the aerobic ones and the total number of aerobic and anaerobic isolates was less in the control group. The anaerobes Bacteroides fragilis and Streptococcus intermedius were isolated from the cervix, amniotic fluid or placenta in 23% and 30% of the PROM patients, respectively. None of the controls harbored B. fragilis, while S. intermedius was isolated from 6.7% of the controls. Group B streptococci were recovered from the mother''s cervix in 20% of the PROM patients and in 6.7% among the controls. Four cases of neonatal septicemia were encountered and another 2 cases were clinically suspected, but not microbiologically verified, contributing to a high perinatal mortality rate (17.6%). Of the PROM patients, 27% developed puerperal infection, while none of the control mothers had such complications. The significance of the anaerobic bacteria and group B streptococci for the maternal and neonatal outcome in cases of PROM is discussed, and a possible etiological role of ascending infection in this complication of pregnancy is postulated.