The impact of elevated blood lead levels in children on maternal health-related quality of life
The impact of elevated blood lead levels in children on maternal health-related quality of life
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DOI：
10.1016/j.chemosphere.2021.130490
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发表时间：
2021-04-21
期刊：
影响因子：
8.8
通讯作者：
Saito, Takeshi
中科院分区：
文献类型：
--
作者：
Nakata, Hokuto;Tohyama, Harukazu;Saito, Takeshi
卡布韦是赞比亚的一个矿业城镇，曾被列为“世界上十大污染最严重的地方”，此前曾发现严重的铅污染。在这项研究中，我们的目的是研究儿童铅中毒的健康相关的生活质量（HRQoL）的母亲在卡布韦的影响。HRQoL进行了评估，使用短表格36调查404名母亲来自40个随机选择的标准查点区（SEAs）的住宅。测量了家庭成员包括母亲本人的血铅水平。母亲与子女的BLL水平呈显著正相关（R = 0.6385，p < 0.0001），学龄前和学龄儿童的BLL水平显著高于母亲和父亲。使用包含家庭成员的BLL、母亲年龄、家庭收入和家庭SEA的数据集，进行逐步多元线性回归分析。结果表明，家庭儿童的代表性BLL和学龄前儿童的BLL与母亲的活力和心理健康得分之间存在显着的负相关。此外，学龄儿童的BLL仅与其母亲的心理健康评分显著相关。相比之下，母亲的BLL与社会角色功能评分之间存在显着的负相关。这表明，无论母亲的BLL如何，儿童BLL升高对其母亲的心理健康状况都有负面影响。(C)2021作者（S）爱思唯尔有限公司出版
Kabwe is a mining town in Zambia that has been ranked among "the ten most polluted places in the world" with previous findings of serious lead (Pb) pollution. In this study, we aim to examine the impact of childhood Pb poisoning on the health-related quality of life (HRQoL) of mothers in Kabwe. The HRQoL was assessed using the Short-Form 36 survey for 404 mothers coming from residences in 40 randomly selected standard enumeration areas (SEAs). Blood lead levels (BLLs) of the household members including the mothers themselves were measured. We found a significant positive correlation between the BLLs of the mothers and their children (R = 0.6385, p < 0.0001), while the BLLs of preschool-aged and school-aged children were significantly higher than those of their mothers and fathers. Using the data sets containing the BLLs of the household members, the age of the mothers, the household income, and the household SEA, we performed stepwise multiple linear regression analyses. The results showed significant negative associations between the representative BLL of household children and the BLL of preschool-aged children with the vitality and mental health scores of their mothers. Additionally, the BLL of school-aged children was only significantly associated with the mental health score of their mothers. By contrast, there was a significant negative association between the BLLs of the mothers with the social role functioning score. This suggests that elevated BLLs in children have a negative impact on the mental health conditions of their mothers regardless of the mothers' BLL. (C) 2021 The Author(s). Published by Elsevier Ltd.