Ionic liquid-based single-drop liquid-phase microextraction combined with high-performance liquid chromatography for the determination of sulfonamides in environmental water
Ionic liquid-based single-drop liquid-phase microextraction combined with high-performance liquid chromatography for the determination of sulfonamides in environmental water
复制标题
离子液体单滴液相微萃取-高效液相色谱法测定环境水中磺胺类药物
DOI：
10.1002/jssc.201100777
复制
发表时间：
2012-02-01
影响因子：
3.1
通讯作者：
Hu, Xialin
中科院分区：
文献类型：
--
作者：
Guo, Xueping;Yin, Daqiang;Hu, Xialin
A simple, rapid and environment-friendly technique of single-drop liquid-phase microextraction has been developed for the determination of sulfonamides in environmental water. Several important parameters including stirring rate, extraction solvent, extraction pH, salinity and extraction time were optimized to maximize the extract efficiency. Extraction solvent 1-octyl-3-methylimidazolium hexafluorophosphate [C8MIM][PF6] ionic liquid showed better extraction efficiency than 1-butyl-3-methylimidazolium hexafluorophosphate [C4MIM][PF6] and 1-octanol. The optimum experimental conditions were: pH, 4.5; sodium chloride content, 36% w/v; extraction time, 20?min. This method provided low detection limits (0.51?ng/mL), good repeatability (the RSD ranging from 4.2 to 9.9%, n=5) and wide linear range (11500?ng/mL), with determination coefficients (r2) higher than 0.9989 for all the target compounds. Real sample analysis showed relative recoveries between 63.5 and 115.8% for all the target compounds.
