Pre-Sleep Casein Protein Ingestion Does Not Impact Next-Day Appetite, Energy Intake and Metabolism in Older Individuals
Pre-Sleep Casein Protein Ingestion Does Not Impact Next-Day Appetite, Energy Intake and Metabolism in Older Individuals
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DOI：
10.3390/nu12010090
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发表时间：
2020-01-01
期刊：
影响因子：
5.9
通讯作者：
Breen, Leigh
中科院分区：
文献类型：
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作者：
Morehen, Stephen;Smeuninx, Benoit;Breen, Leigh
保持足够的每日蛋白质摄入量对于在整个生命周期中保持肌肉质量非常重要。在这方面，过夜期间已被确定为增加老年人蛋白质摄入量的机会之窗。然而，目前尚不清楚睡前蛋白质摄入量是否会影响第二天早上的食欲，从而影响蛋白质摄入量。因此，本研究的目的是研究睡前蛋白质饮料对第二天早上食欲，能量摄入和代谢的影响。12名老年人（8名男性，4名女性;年龄：71.3 ± 4.2岁）参加了一项单盲随机交叉研究。标准化晚餐后，参与者在睡前饮用40克蛋白质饮料，等热量麦芽糊精饮料或安慰剂水对照。第二天早上的食欲，能量摄入，静息代谢率（RMR），呼吸交换率（RER），血浆酰化生长激素释放肽，瘦素，葡萄糖和胰岛素浓度进行了评估。早餐时的食欲和能量摄入没有观察到组间差异。此外，任何治疗组之间的RMR、RER和评估的血液标志物均无显著差异。睡前蛋白质摄入量不会影响第二天早上的食欲和能量摄入量，因此是增加老年人每日蛋白质摄入量的可行策略。
Maintaining adequate daily protein intake is important to maintain muscle mass throughout the lifespan. In this regard, the overnight period has been identified as a window of opportunity to increase protein intake in the elderly. However, it is unknown whether pre-sleep protein intake affects next-morning appetite and, consequently, protein intake. Therefore, the purpose of the current study was to investigate the effects of a pre-sleep protein drink on next-morning appetite, energy intake and metabolism. Twelve older individuals (eight males, four females; age: 71.3 +/- 4.2 years) took part in a single-blind randomised cross-over study. After a standardised dinner, participants consumed either a 40-g protein drink, isocaloric maltodextrin drink, or placebo water control before bedtime. Next-morning appetite, energy intake, resting metabolic rate (RMR), respiratory exchange rate (RER), and plasma acylated ghrelin, leptin, glucose, and insulin concentrations were assessed. No between-group differences were observed for appetite and energy intake at breakfast. Furthermore, RMR, RER, and assessed blood markers were not significantly different between any of the treatment groups. Pre-sleep protein intake does not affect next-morning appetite and energy intake and is therefore a viable strategy to increase daily protein intake in an older population.