Human immunodeficiency virus and the central nervous system
Human immunodeficiency virus and the central nervous system
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DOI：
10.1590/s1413-86702006000100009
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发表时间：
2006-02-01
影响因子：
3.4
通讯作者：
Ellis, Ron
中科院分区：
文献类型：
--
作者：
Almeida, Sergio Monteiro de;Letendre, Scott;Ellis, Ron
艾滋病毒/艾滋病的流行继续与日俱增。妇女、静脉注射吸毒者和少数民族中的发病病例是艾滋病毒感染者中增长最快的部分，50岁以上的艾滋病毒感染者人数正在迅速增加。今天，中枢神经系统和免疫系统被视为艾滋病毒感染的主要目标。近年来，在艾滋病的知识和治疗方面取得了重大进展。与HIV直接相关的神经系统表现为急性病毒性脑膜炎、慢性脑膜炎、HIV相关性痴呆（HAD）、空泡性脊髓病和周围神经系统受累。
The pandemic of HIV/AIDS continues to grow daily. Incident cases among women, intravenous drug users and ethnic minorities comprise the fastest growing segment of the HIV-infected population, and the number of HIV-infected individuals over the age of 50 is growing rapidly. Today, the central nervous system and the immune system are seen as main targets of HIV infection. Significant progress in the knowledge and treatment of AIDS has been obtained in recent years. The neurological manifestations directly related to HIV are acute viral meningitis, chronic meningitis, HIV-associated dementia (HAD), vacuolar myelopathy, and involvement of the peripheral nervous system.