Electrolyte and Water Excretion in Arterial Hypertension: II. Studies in Subjects with Essential Hypertension after Antihypertensive Drug Treatment
Electrolyte and Water Excretion in Arterial Hypertension: II. Studies in Subjects with Essential Hypertension after Antihypertensive Drug Treatment
复制标题
动脉高血压中的电解质和水排泄：II。
作者：
W. Hollander;W. E. Judson
高血压患者增加的钠排泄能力往往通过有效的降压药物治疗而降低。钠排泄的减少并不一定与肾血流动力学功能或静息钠排泄的改变有关。它似乎是由肾小管活动改变引起的。研究结果表明，动脉压本身可能控制钠排泄。它们也与假设一致，即动脉高血压患者钠排泄的某些紊乱可能是血压升高的结果，而不一定是血压升高的原因。
The increased capacity of hypertensive subjects to excrete sodium is frequently reduced by effective antihypertensive drug treatment. This reduction in sodium excretion is not necessarily associated with changes in renal hemodynamic function or resting sodium excretion. It appears to result from an alteration in renal tubular activity. The findings suggest that the arterial pressure per se may operate to control sodium excretion. They also are consistent with the hypothesis that certain disturbances in sodium excretion in arterial hypertension may be the result and not necessarily the cause of an elevated blood pressure.