Smoking and abdominal obesity -: Risk factors for venous thromboembolism among middle-aged Men:: "The study of men born in 1913"
Smoking and abdominal obesity -: Risk factors for venous thromboembolism among middle-aged Men:: "The study of men born in 1913"
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DOI：
10.1001/archinte.159.16.1886
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发表时间：
1999-09-13
影响因子：
--
通讯作者：
Wilhelmsen, L
中科院分区：
文献类型：
--
作者：
Hansson, PO;Ericksson, H;Wilhelmsen, L
背景资料：深静脉血栓形成和肺栓塞的危险因素大多来自于住院患者的病例对照研究，很少有长期的基于人群的研究。目的：研究中年男性深静脉血栓形成和肺栓塞的长期危险因素。设计：前瞻性队列研究。设置：一般社区，“1913年出生的男性研究”。“科目：一个随机的人口样本855名男子，所有年龄50岁的basel.Main结果Measures：八百五十五名男子参加了在1963年在50岁的筛选检查，并在1967年在54岁的这些男子中的792人进行了复查。所有的男性都接受了定期检查，直到80岁。客观的方法被用来确定深静脉血栓形成或肺embolis.Results的诊断：腰围（P= 0.004）和吸烟（P= 0.02）预测在多变量生存分析的静脉血栓栓塞事件。腰围最高十分位数（大于或等于100 cm）的男性校正后的相对危险度为3.92（95%置信区间，2.10-7.29; P
Background: Risk factors for deep vein thrombosis and pulmonary embolism are mostly derived from case-control studies of hospitalized patients, and there are few long-term population-based studies.Objective: To study the long-term risk factors for deep vein thrombosis and pulmonary embolism among middle-aged men.Design: A prospective cohort study.Setting: General community, "The Study of Men Born in 1913."Subjects: A random population sample of 855 men, all aged 50 years at baseline.Main Outcome Measures: Eight-hundred fifty-five men participated in a screening examination in 1963 at the age of 50 years, and 792 of these men were reexamined in 1967 at the age of 54. All the men were followed up with periodic examinations until the age of 80. Objective methods were used to ascertain a diagnosis of deep vein thrombosis or pulmonary embolism.Results: Waist circumference (P=.004) and smoking (P=.02) predicted a venous thromboembolic event in multivariate survival analysis. Men in the highest decile of waist circumference (greater than or equal to 100 cm) had an adjusted relative risk of 3.92 (95% confidence interval, 2.10-7.29; P