MIRD Pamphlet No. 26: Joint EANM/MIRD Guidelines for Quantitative 177Lu SPECT Applied for Dosimetry of Radiopharmaceutical Therapy
MIRD Pamphlet No. 26: Joint EANM/MIRD Guidelines for Quantitative 177Lu SPECT Applied for Dosimetry of Radiopharmaceutical Therapy
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DOI：
10.2967/jnumed.115.159012
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发表时间：
2016-01-01
影响因子：
9.3
通讯作者：
Walrand, Stephan
中科院分区：
文献类型：
--
作者：
Ljungberg, Michael;Celler, Anna;Walrand, Stephan
在个体化内部放射性核素治疗中的吸收剂量计算的准确性与在每个成像时间点获得的活性（或活性浓度）估计的准确性直接相关。MIRD第23号小册子介绍了定量SPECT成像所需方法的概述。本文件是遵循MIRD 23中提供的一般信息的一系列特定同位素指南和建议中的下一个。本文主要介绍Lu-177及其在放射性药物治疗中的应用。
The accuracy of absorbed dose calculations in personalized internal radionuclide therapy is directly related to the accuracy of the activity (or activity concentration) estimates obtained at each of the imaging time points. MIRD Pamphlet no. 23 presented a general overview of methods that are required for quantitative SPECT imaging. The present document is next in a series of isotope-specific guidelines and recommendations that follow the general information that was provided in MIRD 23. This paper focuses on Lu-177 (lutetium) and its application in radiopharmaceutical therapy.