Evaluation of Pulmonary Structure and Function in Patients with Cystic Fibrosis from Electrical Impedance Tomography Data.

Evaluation of Pulmonary Structure and Function in Patients with Cystic Fibrosis from Electrical Impedance Tomography Data.
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根据电阻抗断层扫描数据评估囊性纤维化患者的肺结构和功能。

DOI:
10.1007/978-1-0716-1803-5_39
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发表时间:
2022
期刊:
Methods in molecular biology (Clifton, N.J.)
影响因子:
--
通讯作者:
Mueller,JenniferL
Mueller,JenniferL
中科院分区:
--
文献类型:
--
作者:
Mueller,JenniferL

文献摘要

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电阻抗断层成像(EIT)是一种医学成像技术,通过皮肤上的电极施加低频、低幅度的电磁场来计算体内的电导率和/或介电常数,并根据重建的值形成函数图像。这项工作描述了计算EIT衍生的肺功能替代测量的方法,并从功能EIT图像中识别空气滞留和固结的区域。这些方法是为患有囊性纤维化的儿科患者开发的,对他们来说,实时非电离成像方式对监测疾病进展或肺恶化有很大好处。
Electrical impedance tomography (EIT) is a medical imaging technique in which low frequency, low amplitude electromagnetic fields applied through electrodes on the skin are used to compute the conductivity and/or permittivity inside the body and form functional images from the reconstructed values. This work describes methods of computing EIT-derived surrogate measures of pulmonary function and identifying regions of air trapping and consolidation from functional EIT images. These methods were developed for pediatric patients with cystic fibrosis, for whom a real-time non-ionizing imaging modality can be of great benefit for monitoring disease progression or a pulmonary exacerbation.