Advances in nanomedicines for malaria treatment
Advances in nanomedicines for malaria treatment
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DOI：
10.1016/j.cis.2013.10.014
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发表时间：
2013-12-01
影响因子：
15.6
通讯作者：
Souto, E. B.
中科院分区：
文献类型：
--
作者：
Aditya, N. P.;Vathsala, P. G.;Souto, E. B.
疟疾是一种主要影响热带国家儿童和孕妇的传染病。每年感染疟疾的人的死亡率很高，成为一个公共卫生问题。导致疟疾成功扩散的主要因素是抗药性寄生虫数量的增加。为了应对这一趋势，已经在纳米技术和纳米医学方面进行了研究，以开发能够掺入药物的新的生物相容性系统，降低耐药性，通过靶向递送为疟疾的诊断、控制和治疗做出贡献。在这篇综述中，我们讨论了与疟疾传播相关的主要问题以及抗疟疾药物递送纳米医学的最新发展。(C)2013爱思唯尔有限公司版权所有。
Malaria is an infectious disease that mainly affects children and pregnant women from tropical countries. The mortality rate of people infected with malaria per year is enormous and became a public health concern. The main factor that has contributed to the success of malaria proliferation is the increased number of drug resistant parasites. To counteract this trend, research has been done in nanotechnology and nanomedicine, for the development of new biocompatible systems capable of incorporating drugs, lowering the resistance progress, contributing for diagnosis, control and treatment of malaria by target delivery. In this review, we discussed the main problems associated with the spread of malaria and the most recent developments in nanomedicine for anti-malarial drug delivery. (C) 2013 Elsevier B.V. All rights reserved.