Value of exercise treadmill testing in women

Value of exercise treadmill testing in women
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DOI:
10.1016/s0735-1097(98)00451-3
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发表时间:
1998-11-15
影响因子:
24
通讯作者:
Peterson, ED
Peterson, ED
中科院分区:
医学1区
文献类型:
--
作者:
Alexander, KP;Shaw, LJ;Peterson, ED

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目标。我们试图确定跑步机评分为女性提供准确诊断和预后风险评估的能力。背景。据报道,跑步机测试诊断女性胸痛的准确性较低。杜克跑步机商店 (DTS) 对女性的诊断和预后价值尚不清楚。方法。我们确定了 DTS 对 976 名女性和 2,249 名男性的诊断和预后价值,这些人从 1984 年到 1994 年在同一机构接受了跑步机测试和心导管插入术。结果。女性和男性在 DTS(1.6 vs. -0.3,p < 0.0001)、疾病患病率(显着冠状动脉疾病 [CAD] 分别为 32% vs. 72%,p < 0.001)和 2 年死亡率(1.9% vs. 4.9%,p < 0.0001)方面存在显着差异。 DTS 提供的信息超出了女性和男性冠心病和生存的临床预测因素。尽管总体而言,女性的生存率更高,但 DTS 在将两性分为预后类别方面表现同样出色。实际上,在排除疾病方面,女性 DTS 的表现优于男性,患有任何严重冠状动脉疾病(大于或等于 1 支血管且狭窄大于或等于 75%)(20% 与 47%,p < 0.001)或严重疾病(3 支血管疾病或大于或等于 75% 左主干狭窄)(3.5% 与 11.4%,p < 0.001)的低风险女性较少。 0.001).结论。通过结合跑步机测试的多个方面,DTS 有效地将女性分为诊断和预后风险类别。 (J Am Coll Cardiol 1998;32:1657-64) (C)1998 年,美国心脏病学会。
Objectives. We sought to determine the ability of a treadmill score to provide accurate diagnostic and prognostic risk estimates in women.Background. Treadmill testing has been reported to have a lower accuracy for diagnosis of chest pain in women. The diagnostic and prognostic value of the Duke Treadmill Store (DTS) in women is unknown.Methods. We determined the diagnostic and prognostic value of the DTS in 976 women and 2,249 men who underwent both treadmill testing and cardiac catheterization in a single institution from 1984 to 1994.Results. Women and men differed significantly in DTS (1.6 vs. -0.3, p < 0.0001), disease prevalence (32% vs. 72% significant coronary artery disease [CAD], p < 0.001), and 2-year mortality (1.9% vs. 4.9%, p < 0.0001). The DTS provided information beyond clinical predictors of both coronary disease and survival in women and men. Although overall women had better survival, the DTS performed equally well in stratifying both genders into prognostic categories. The DTS actually performed better in women than in men for excluding disease, with fewer low risk women having any significant coronary disease (greater than or equal to 1 vessel with greater than or equal to 75% stenosis) (20% vs. 47%, p < 0.001), or severe disease (3-vessel disease or greater than or equal to 75% left main stenosis) (3.5% vs. 11.4%, p < 0.001).Conclusions. By combining several aspects of treadmill testing, the DTS effectively stratifies women into diagnostic and prognostic risk categories. (J Am Coll Cardiol 1998;32:1657-64) (C)1998 by the American College of Cardiology.