Contrast gain control in auditory cortex.
Contrast gain control in auditory cortex.
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DOI：
10.1016/j.neuron.2011.04.030
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发表时间：
2011-06-23
期刊：
影响因子：
16.2
通讯作者：
King AJ
中科院分区：
文献类型：
--
作者：
Rabinowitz NC;Willmore BD;Schnupp JW;King AJ
听觉系统必须代表具有广泛统计特性的声音。一个重要的特性是声环境中的光谱时间对比：相对于平均压力，每个频带中声压的变化。我们表明，雪貂听觉皮层的神经元重新调整其增益，以部分补偿最近刺激的光谱时间对比。当对比度较低时，神经元增加其增益，对刺激的微小变化变得更加敏感，尽管对比度增益控制的有效性在低平均水平下降低。增益主要是由每个神经元首选频率附近的对比度决定的，但也有来自较远频段对比度的贡献。神经反应通过对比在约100 ms的时间尺度上进行调节。通过使用对比度增益控制来扩展或压缩其输入的表示，听觉系统可能正在寻求自然声音的有效编码。►增益是由频谱局部和全局对比度的组合决定的►在有限的范围内，平均刺激水平也会影响神经增益►对比度增益控制很快（约100毫秒）；增益减少比增益增加快
The auditory system must represent sounds with a wide range of statistical properties. One important property is the spectrotemporal contrast in the acoustic environment: the variation in sound pressure in each frequency band, relative to the mean pressure. We show that neurons in ferret auditory cortex rescale their gain to partially compensate for the spectrotemporal contrast of recent stimulation. When contrast is low, neurons increase their gain, becoming more sensitive to small changes in the stimulus, although the effectiveness of contrast gain control is reduced at low mean levels. Gain is primarily determined by contrast near each neuron's preferred frequency, but there is also a contribution from contrast in more distant frequency bands. Neural responses are modulated by contrast over timescales of ∼100 ms. By using contrast gain control to expand or compress the representation of its inputs, the auditory system may be seeking an efficient coding of natural sounds. ► We find evidence for spectrotemporal contrast gain control in auditory cortex ► Gain is determined by a combination of spectrally local and global contrast ► Within a limited range, mean stimulus level also affects neural gain ► Contrast gain control is fast (∼100 ms); gain decreases are faster than increases
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影响因子：
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作者：
ATTNEAVE, F
通讯作者：
ATTNEAVE, F
DOI：
10.1523/jneurosci.5475-09.2010
发表时间：
2010-04-07
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
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作者：
Bizley JK;Walker KM;King AJ;Schnupp JW
通讯作者：
Schnupp JW
DOI：
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发表时间：
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期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
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通讯作者：
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