One‐Pot Synthesis of Functionalized 3‐Aryl‐1‐phenyl‐1H‐pyrazoles from Hydrazonoyl Chlorides and Acetylenic Esters in the Presence of Ph3P
One‐Pot Synthesis of Functionalized 3‐Aryl‐1‐phenyl‐1H‐pyrazoles from Hydrazonoyl Chlorides and Acetylenic Esters in the Presence of Ph3P
复制标题
Ph3P存在下，腙酰氯和乙酯一锅法合成功能化3-芳基-1-苯基-1H-吡唑
DOI：
10.1002/hlca.200900246
复制
发表时间：
2010
影响因子：
1.8
通讯作者：
A. Mirzaei
中科院分区：
文献类型：
--
作者：
I. Yavari;Gholamhossein Khalili;A. Mirzaei
两性离子1：1的中间体由Ph 3 P加成到炔酸酯上产生，被1-[（芳基）氯亚甲基]-2-苯肼（= N-苯基芳烃甲肼酰氯）捕获，以良好的产率得到官能化的3-芳基-1-苯基-1H-吡唑。
The zwitterionic 1 : 1 intermediates generated by addition of Ph3P to acetylenic esters is trapped by 1-[(aryl)chloromethylene]-2-phenylhydrazines (=N-phenylarenecarbohydrazonoyl chlorides) to yield functionalized 3-aryl-1-phenyl-1H-pyrazoles in good yields.