Neuronal dynamics of predictive coding
Neuronal dynamics of predictive coding
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DOI：
10.1177/107385840100700605
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发表时间：
2001-12-01
期刊：
影响因子：
5.6
通讯作者：
Mehta, MR
中科院分区：
文献类型：
--
作者：
Mehta, MR
中枢神经系统的一项关键任务是学习刺激之间的因果关系，以预测未来的事件，例如移动的猎物或捕食者的位置。预期背后的神经元现象是什么？在这篇文章中，我回顾了最近海马电生理学的研究结果，这些研究结果阐明了这个问题。结果表明，海马空间感受野在放电特性上表现出大而快速的预期变化。这些变化是经验和环境依赖的，可以通过基于nmda依赖的突触可塑性的计算模型来解释。在广泛不同的神经回路，如海马体和初级视觉皮层的预期网络动力学之间惊人的相似性进行了讨论。这些实验和理论结果表明，突触可塑性的微观规律如何引起接受野和行为的突现预期特性。
A critical task of the central nervous system is to learn causal relationships between stimuli to anticipate events in the future, such as the position of a moving prey or predator. What are the neuronal phenomena underlying anticipation? In this article, I review recent results in hippocampal electrophysiology that shed light on this issue. It is shown that hippocampal spatial receptive fields show large and rapid anticipatory changes in their firing characteristics. These changes are experience- and environment-dependent and can be explained by a computational model based on NMDA-dependent synaptic plasticity during behavior. Striking similarities between the anticipatory network dynamics of widely different neural circuits, such as the hippocampus and primary visual cortex, are discussed. These experimental and theoretical results indicate how the microscopic laws of synaptic plasticity give rise to emergent anticipatory properties of receptive fields and behavior.