Morphometric analysis of the brain vesicles during the human embryonic period by magnetic resonance microscopic imaging
Morphometric analysis of the brain vesicles during the human embryonic period by magnetic resonance microscopic imaging
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DOI：
10.1111/j.1741-4520.2011.00345.x
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发表时间：
2012-03-01
影响因子：
1.3
通讯作者：
Takakuwa, Tetsuya
中科院分区：
文献类型：
--
作者：
Nakashima, Takashi;Hirose, Ayumi;Takakuwa, Tetsuya
使用来自京都人类胚胎保藏中心的 177 个磁共振图像数据，对卡内基阶段 (CS) 17 和 23 之间脑泡的发育进行了形态测量。 CS17 时整个胚胎体积为 106.55 +/- 21.08 mm3，当达到 1357.28 +/- 392.20 mm3 时，呈指数增加到 CS23。 CS17 时脑泡长度为 29.83 +/- 2.52 mm，几乎呈线性增加，并在 CS23 时达到 49.31 +/- 6.66 mm。背侧的增加率大约是腹侧的4.2倍。脑泡长度的增加主要来自于前脑的长度，前脑背侧的增加速度是腹侧的3倍。
The development of the brain vesicles between Carnegie stages (CS) 17 and 23 was analyzed morphometrically using 177 magnetic resonance image data derived from the Kyoto Collection of Human Embryos. Whole embryonic volume was 106.55 +/- 21.08 mm3 at CS17, exponentially increasing to CS23 when it reached 1357.28 +/- 392.20 mm3. Length of brain vesicles was 29.83 +/- 2.52 mm at CS17, increased almost linearly and reached 49.31 +/- 6.66 mm at CS23. The rate of increase was approximately 4.2 times higher on the dorsal side than on the ventral side. The increase in the length of the brain vesicles resulted mainly from that of the prosencephalon, and the rate of increase was three times higher on the dorsal side than on the ventral side of the prosencephalon.