Relationship between the MIC of vancomycin and clinical outcome in patients with MRSA nosocomial pneumonia
Relationship between the MIC of vancomycin and clinical outcome in patients with MRSA nosocomial pneumonia
复制标题
DOI：
10.1007/s00134-011-2130-7
复制
发表时间：
2011-04-01
影响因子：
38.9
通讯作者：
Hong, Sang-Bum
中科院分区：
文献类型：
--
作者：
Choi, Eun Young;Huh, Jin Won;Hong, Sang-Bum
目的：本研究的目的是评估耐甲氧西林金黄色葡萄球菌（MRSA）分离株中万古霉素最低抑菌浓度（MIC）的分布，并评价万古霉素相对于万古霉素MIC在患有MRSA医院内肺炎的成人患者中的疗效。方法：这项回顾性队列研究涉及万古霉素治疗的MRSA医院获得性肺炎成人。使用Etest测定万古霉素MIC。MRSA和万古霉素MIC>= 1.5 μ g/mL的患者以及MRSA和MIC
Purpose: The objective of this study is to assess the distribution of vancomycin minimum inhibitory concentrations (MICs) in methicillin-resistant Staphylococcus aureus (MRSA) isolates and evaluate the efficacy of vancomycin relative to vancomycin MICs in adult patients with MRSA nosocomial pneumonia. Methods: This retrospective cohort study involved adults with MRSA nosocomial pneumonia treated with vancomycin. Vancomycin MICs were determined using Etest. Patients with MRSA and vancomycin MICs >= 1.5 mu g/mL and those with MRSA and MICs