Pharmacokinetics of new nootropic acylprolyldipeptide and its penetration across the blood-brain barrier after oral administration
Pharmacokinetics of new nootropic acylprolyldipeptide and its penetration across the blood-brain barrier after oral administration
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DOI：
10.1007/bf02439270
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发表时间：
2000-04-01
影响因子：
0.7
通讯作者：
Seredenin, SB
中科院分区：
文献类型：
--
作者：
Boiko, SS;Ostrovskaya, RU;Seredenin, SB
Pharmacokinetics of GVS-111, a new acylprolyldipeptide with nootropic properties and its penetration across the blood-brain barrier were studied in rats using HPLC. It was found that the dipeptide is absorbed in the gastrointestinal tract, enters the circulation, and penetrates through the blood-brain barrier in an umodified state.
