Surgical treatment of solid hemangioblastomas of the posterior fossa: A report of 28 cases.
Surgical treatment of solid hemangioblastomas of the posterior fossa: A report of 28 cases.
复制标题
后颅窝实性血管母细胞瘤28例手术治疗报告
DOI：
10.3892/ol.2016.5531
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发表时间：
2017-03
期刊：
影响因子：
2.9
通讯作者：
Wang Y
中科院分区：
文献类型：
--
作者：
Cui H;Zou J;Bao YH;Wang MS;Wang Y
本研究评估了28例诊断为后窝高血管病变的实体血管母细胞瘤的临床特征、治疗策略和结果。术前对供血动脉进行栓塞治疗效果有限，仅有7例患者因术中出血减少而受益。所有患者肿瘤全部切除，22例完全康复，6例复发，均为van Hippel Lindau病。本研究表明，细致的整体手术切除是治疗后窝实体血管母细胞瘤的最佳方法。对于大肿瘤，术前栓塞是预防术后并发症的关键。随着显微外科技术的进步和对肿瘤血管形态的了解，可以实现低死亡率的肿瘤全切除。
This study evaluated the clinical features, treatment strategies and outcomes of solid hemangioblastomas in 28 patients diagnosed with hypervascular lesions in the posterior fossa. Preoperative embolization of the feeding arteries had limited effects, with only 7 patients benefitting from it for the reduction of intraoperative hemorrhage. The tumor was completely removed in all patients, and 22 patients had a full recovery, while 6 patients, all of whom had van Hippel Lindau disease, developed recurrences. The present study demonstrated that meticulous en bloc surgical resection was the optimal treatment for solid hemangioblastomas of the posterior fossa. For large tumors, preoperative embolization was critical for preventing postoperative morbidity. Given the improvements in microsurgical techniques and the understanding of the tumor vascular pattern, total tumor removal associated with a low mortality rate could be achieved.