FURTHER-STUDIES ON STEROIDAL GLYCOSIDES FROM BULBS, ROOTS AND LEAVES OF ALLIUM-SATIVUM L
FURTHER-STUDIES ON STEROIDAL GLYCOSIDES FROM BULBS, ROOTS AND LEAVES OF ALLIUM-SATIVUM L
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DOI：
10.1248/cpb.37.2741
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发表时间：
1989-10-01
影响因子：
1.7
通讯作者：
FUWA, T
中科院分区：
文献类型：
--
作者：
MATSUURA, H;USHIROGUCHI, T;FUWA, T
从大蒜鳞茎中分离得到一个新的呋喃甾醇糖苷(2)和大蒜皂苷-B1，以及原去半乳糖苷(3)。2的结构确定为(25R)-26-O-.beta.-D-glucopyranosyl-22-hydroxy-5.alpha.-furostane-3.beta.，6.beta.，26-triol 3-O-β-D-吡喃葡萄糖基-(1.fwdarw.2)-O-[β-D-吡喃葡萄糖基-(1.fwdarw.2)-O-β-D-吡喃葡萄糖基-(1.fwdarw.4)-O-β-D-半乳糖苷。从该植物根中分离得到两个新的甾体苷，分别命名为Sativoside-R1(16)和Sativoside-R2(15)，其结构为(25R)-26-O-.beta.-D-glucopyranosyl-22-hydroxy-5.alpha.-furostane-3.beta.，26-diol 3-O-β-D-葡萄糖苷-(1.fwdarw)。3)-O-β-D-吡喃葡萄糖基-(1.fwdarw.2)-O-[β-D-木吡喃糖基-(1.fwdarw.3)-O-β-D-吡喃葡萄糖基-(1.fwdarw.4)-O-β-D-半乳糖苷(16)及其对应的螺甾醇糖苷(15)。除这些糖苷外，还分离鉴定了3个已知的糖苷类化合物，3个去半乳糖苷(13)和14个F-皂苷(14)。薄层层析未检测到大蒜叶中的一个糖苷组分，未检测到甾体苷。
A new furostanol glycoside (2), and sativoside-B1, was isolated from garlic, bulbs of Allium sativum L., along with proto-desgalactotigonin (3). The structure of 2 was established to be (25R)-26-O-.beta.-D-glucopyranosyl-22-hydroxy-5.alpha.-furostane-3.beta.,6.beta.,26-triol 3-O-.beta.-D-glucopyranosyl-(1 .fwdarw. 2)-O-[.beta.-D-glucopyranosyl-(1 .fwdarw. 2)]-O-.beta.-D-glucopyranosyl-(1 .fwdarw. 4)-O-.beta.-D-galactopyranoside. From roots of this plant, two new steroidal glycosides, named sativoside-R1 (16) and sativoside-R2 (15) were isolated and their structures were determined to be (25R)-26-O-.beta.-D-glucopyranosyl-22-hydroxy-5.alpha.-furostane-3.beta.,26-diol 3-O-.beta.-D-glucopyranosyl-(1 .fwdarw. 3)-O-.beta.-D-glucopyranosyl-(1 .fwdarw. 2)-O-[.beta.-D-xylopyranosyl-(1 .fwdarw. 3)]-O-.beta.-D-glucopyranosyl-(1 .fwdarw. 4)-O-.beta.-D-galactopyranoside (16) and its corresponding spirostanol glycoside (15). Besides these glycosides, three known glycosides, 3 desgalactotigonin (13) and F-gitonin (14) were isolated and identified. In a glycoside fraction of the leaves of A. sativum, steroidal glycosides were not detected by thin layer chromatography analysis.