The Types of Neurological Deficits Might Not Justify Withholding Treatment in Patients With Low Total National Institutes of Health Stroke Scale Scores
The Types of Neurological Deficits Might Not Justify Withholding Treatment in Patients With Low Total National Institutes of Health Stroke Scale Scores
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DOI：
10.1161/strokeaha.111.620674
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发表时间：
2012-03-01
期刊：
影响因子：
8.3
通讯作者：
Adams, Harold P., Jr.
中科院分区：
文献类型：
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作者：
Leira, Enrique C.;Ludwig, Bryan R.;Adams, Harold P., Jr.
背景和目的：对于轻度卒中患者的治疗阈值存在争议。如果医生认为这些症状不会致残，他们通常会停止对这些患者的急性治疗。我们通过分析美国国立卫生研究院卒中量表（NIHSS）评分中的特定神经功能缺损与NIHSS总评分低的患者的长期结局之间的关系来测试这种做法的适当性。我们对入组ORG 10172急性卒中治疗试验的患者进行了二次分析，这些患者在症状发作后4.5小时内出现，并且基线NIHSS评分
Background and Purpose-There is controversy regarding the threshold for treating patients with mild strokes. Physicians often withhold acute treatment in these patients if they perceive the symptoms are not going to be disabling. We tested the appropriateness of this practice by analyzing the relationship between specific neurological deficits in the National Institutes of Health Stroke Scale (NIHSS) score and long-term outcome among patients with a low total NIHSS score.Methods-We performed a secondary analysis on those patients enrolled in the Trial of ORG 10172 in Acute Stroke Treatment that presented within 4.5 hours of symptom onset and had a baseline NIHSS score