The use of chloramphenicol and foster mothers in the control of natural pasteurellosis in experimental mice.
The use of chloramphenicol and foster mothers in the control of natural pasteurellosis in experimental mice.
复制标题
使用氯霉素和养母控制实验小鼠的自然巴氏杆菌病。
DOI：
10.1038/icb.1953.19
复制
发表时间：
1953
期刊：
影响因子：
--
通讯作者：
A. L. Campbell
中科院分区：
文献类型：
--
作者：
D. F. Gray;A. L. Campbell
在澳大利亚有小鼠嗜肺巴氏杆菌感染的记录。发生这种情况的最可能的解释似乎是，当C57黑老鼠被引入该国时，它作为一种潜伏感染而存在。两年多来没有证据表明它在殖民地存在。我们的经验表明，这种微生物除了潜伏感染外，还可能在成年繁殖小鼠及其窝仔中引起自然流行，导致不育、慢性肺炎和死亡。目前还没有证据表明这种病毒会传播到与进口老鼠密切接触的兔子或豚鼠中，但当地老鼠在3年后显示出潜伏感染的证据。使用氯霉素和养母，以消除感染的描述。
Pasteurella pneumotropicainfection in mice is recorded in Australia. The most probable explanation for its occurrence would appear to be that it existed as a latent infection when C57 black mice were introduced into the country. There was no evidence of its presence in the colony for more than two years. That this organism, in addition to latent infection, may cause a natural epidemic in adult breeding mice and their litters with sterility, chronic pneumonia and death is shown by our experience. There is no evidence at present of spread to rabbits or guinea-pigs kept in close proximity to the imported mice, but local mice showed evidence of latent infection after 3 years. The use of chloramphenicol and of foster mothers to eliminate the infection is described.