Hybridization chain reaction triggered controllable one-dimensional assembly of gold nanoparticles
Hybridization chain reaction triggered controllable one-dimensional assembly of gold nanoparticles
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杂交链式反应引发金纳米粒子的可控一维组装
DOI：
10.1007/s11426-015-0529-8
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发表时间：
2016
期刊：
影响因子：
--
通讯作者：
Huang Chengzhi
中科院分区：
文献类型：
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作者：
Wang Jian;Du Yuqing;Lie Shaoqing;Huang Chengzhi
将纳米材料组装和排列成理想的图案是相当重要的，因为纳米材料的性质不仅取决于尺寸和形状，而且还取决于集体构件之间的空间排列。本研究利用杂交链式反应（HCR）中的DNA自组装技术，通过将金纳米粒子（AuNPs）沿着dsDNA的骨架进行一维组装，制备出长双链DNA（dsDNA）。有趣的是，通过调节HCR的反应时间，可以实现沿沿着dsDNA链的AuNPs组装体的可调长度，这是基于Au与DNA的-SH基团之间的共价键的形成。与单个金纳米粒子的弱光散射相比，这些金纳米粒子组装体在暗视野显微镜下可以清晰成像，表明组装后的光散射得到了极大的改善。
Assembling and ordering nanomaterials into desirable patterns are considerably significant, since the properties of nanomaterials depend not only on the size and shape, but also on the spatial arrangement among the collective building blocks. In this work, the DNA self-assembly technology of hybridization chain reaction (HCR) provided a convenient method to yield long double-strand DNA (dsDNA) to install gold nanoparticles (AuNPs) into one dimensional assembly along the skeleton of dsDNA. Interestingly, the tunable length of AuNPs assemblies along dsDNA chain could be achieved by adjusting the reaction time of HCR, which is based on the formation of covalent bond between Au and the -SH group of DNA. Compared with weak light scattering of single AuNP, these AuNPs assemblies could be clearly imaged under the dark field microscopy, indicating that the light scattering was greatly improved after assembling.