Aspirin inhibition of platelet deposition at angioplasty sites: demonstration by platelet scintigraphy.
Aspirin inhibition of platelet deposition at angioplasty sites: demonstration by platelet scintigraphy.
复制标题
阿司匹林抑制血管成形术部位的血小板沉积：血小板闪烁扫描证实。
DOI：
10.1148/radiology.151.2.6231656
复制
发表时间：
1984
期刊：
影响因子：
19.7
通讯作者：
Welch,MJ
中科院分区：
文献类型：
--
作者：
Cunningham,DA;Kumar,B;Siegel,BA;Gilula,LA;Totty,WG;Welch,MJ
在一项17名男性的非随机研究中，使用In-111血小板造影术评价既往阿司匹林给药对髂动脉、股动脉或腘动脉腔内血管成形术所致动脉损伤部位In-111标记的自体血小板蓄积的影响。在血管成形术前4天内接受不同剂量阿司匹林的9名男性中，血管成形术部位的血小板定位程度显著低于至少两周未接受阿司匹林的8名男性。我们的研究结果表明，阿司匹林治疗血管成形术前限制早期血小板沉积在血管成形术网站的男性。
In-111 platelet scintigraphy was used to evaluate the effects of prior aspirin administration on the accumulation of In-111-labeled autologous platelets at sites of arterial injury resulting from iliac, femoral, or popliteal transluminal angioplasty in a nonrandomized study of 17 men. The degree of platelet localization at angioplasty sites was significantly less in nine men who had received aspirin in varying doses within the 4 days before angioplasty than in eight men who had not received aspirin for at least two weeks. Our results suggest that aspirin treatment before angioplasty limits the early platelet deposition at the angioplasty site in men.