Deep Lamellar Keratoplasty in the Treatment of Keratoconus
Deep Lamellar Keratoplasty in the Treatment of Keratoconus
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DOI：
10.1159/000091759
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发表时间：
2006-05
期刊：
影响因子：
2.6
通讯作者：
N. Pakrou;S. Fung;D. Selva;Mark Chehade;I. Leibovitch
中科院分区：
文献类型：
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作者：
N. Pakrou;S. Fung;D. Selva;Mark Chehade;I. Leibovitch
目的：介绍我们对一系列接受深板层角膜移植术 (DLK) 治疗圆锥角膜 (KC) 的患者的经验。设计：单一外科医生、前瞻性、连续系列。方法：该研究包括 1999 年 3 月至 2003 年 11 月期间在皇家阿德莱德医院接受 DLK 的所有 KC 患者。评估的参数包括患者的人口统计数据、术前和术后最佳矫正视力、术后角膜曲率以及术中和术后并发症。结果：患者22例（23只眼）； 10 名女性和 12 名男性，平均年龄为 35 ± 13 岁（中位数，33.5；范围，17-73）。中位随访期为 13 个月（范围 7-38 个月）。在 89% (16/18) 接受 DLK 且可以获得视力的眼睛中，记录到的最佳矫正视力至少为 6/12。有两次后弹力层穿孔（8.7%），其中手术转为穿透性角膜移植术，无并发症。一名患者出现双前房，该病自行消退，没有产生任何后果。结论：我们的系列中看到的视觉结果和并发症发生率与最近发表的文献相当。因此，DLK 可以被认为是 KC 手术治疗穿透性角膜移植术的合适替代方案。
Purpose: To present our experience with a series of patients treated with deep lamellar keratoplasty (DLK) for keratoconus (KC). Design: A single surgeon, prospective, consecutive series.Method: The study included all patients with KC who underwent DLK between March 1999 and November 2003 at the Royal Adelaide Hospital. The parameters evaluated included patients’ demographics, pre- and post-operative best corrected visual acuities, post-operative keratometry, and intra- and post-operative complications. Results: There were 22 patients (23 eyes); 10 females and 12 males, with a mean age of 35 ± 13 years (median, 33.5; range, 17–73). The median follow-up period was 13 months (range 7–38). In 89% (16/18) of eyes which underwent DLK, and in which a visual acuity could be obtained, a best corrected visual acuity of at least 6/12 was recorded. There were two episodes of Descemet’s membrane perforation (8.7%), in which the procedure was converted to penetrating keratoplasty without complications. One patient developed a double anterior chamber, which resolved spontaneously without consequences. Conclusion: The visual outcomes and complication rates seen in our series are comparable to the recent published literature. Hence DLK can be considered as a suitable alternative to penetrating keratoplasty for the surgical treatment of KC.