Clinical and investigative profile of biopsy-proven sarcoid uveitis in India
Clinical and investigative profile of biopsy-proven sarcoid uveitis in India
复制标题
DOI：
10.1080/09273940801904150
复制
发表时间：
2008-01-01
影响因子：
3.3
通讯作者：
Agarwal, Manisha
中科院分区：
文献类型：
--
作者：
Ganesh, Sudha K.;Agarwal, Manisha
目的：回顾性分析经组织病理学证实的结节病葡萄膜炎病例的临床特征、研究概况、治疗反应和最终视力结果。研究方法：回顾性病例系列分析9例15只眼，1999年7月1日至2003年8月之间，活检证实结节性葡萄膜炎。男3例，女6例。平均就诊年龄为44.1岁（范围11-62岁），平均随访时间为28.4个月。结果：6例患者双眼受累，3例单侧受累。9例患者中有5例主要累及眼部。最常见的表现是中间葡萄膜炎和肉芽肿性前葡萄膜炎7例。9例患者中有8例对全身和眼周类固醇药物治疗反应良好。结论：眼部病变是系统性结节病的主要表现。在亚洲印度人群中，肉样瘤性葡萄膜炎通常表现为中间葡萄膜炎伴肉芽肿性前葡萄膜炎。
Purpose: Retrospective analysis of the clinical features, investigative profile, response to treatment, and final visual outcome in histopathologically confirmed cases of sarcoid uveitis. Methods: Retrospective case series analysis was done of 15 eyes of 9 patients seen between July 1 999 and August 2003 with biopsy-proven sarcoid uveitis. There were 3 were males and 6 females. The mean age at presentation was 44.1 years (range 11-62 years), The mean follow-up was 28.4 months. Results: Six patients had bilateral ocular involvement and 3 had unilateral involvement. Five out of 9 patients had primarily ocular involvement. The most common presentation was intermediate uveitis and granulomatous anterior uveitis in 7 patients. Eight of 9 patients responded well to the medical treatment with systemic and periocular steroids. Conclusions: Ocular lesions can be the primary manifestation of systemic sarcoidosis. Sarcoid uveitis in the Asian Indian population often presents an intermediate uveitis with granulomatous anterior uveitis.