Changes in Residential Proximity to Road Traffic and the Risk of Death From Coronary Heart Disease
Changes in Residential Proximity to Road Traffic and the Risk of Death From Coronary Heart Disease
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DOI：
10.1097/ede.0b013e3181e89f19
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发表时间：
2010-09-01
期刊：
影响因子：
5.4
通讯作者：
Brauer, Michael
中科院分区：
文献类型：
--
作者：
Gan, Wen Qi;Tamburic, Lillian;Brauer, Michael
背景：居民区靠近道路交通与冠心病(CHD)发病率和死亡率增加有关。然而，目前尚不清楚居民交通距离的变化是否会改变冠心病死亡的风险。方法：我们使用了一项基于人群的队列研究，暴露时间为5年，随访期为4年，以探索居民交通距离的变化与冠心病死亡风险之间的关系。队列包括所有45-85岁的居民，他们在暴露期间居住在温哥华大都市，基线时没有已知的冠心病(n=450,283)。住宅与交通的接近程度是使用地理信息系统估计的。使用省级死亡登记数据库确定随访期内的冠心病死亡。结果：在9年的研究期间，与那些一直远离道路交通(高速公路150米或主干道50米)的受试者相比，那些一直居住在靠近交通的受试者(
Background: Residential proximity to road traffic is associated with increased coronary heart disease (CHD) morbidity and mortality. It is unknown, however, whether changes in residential proximity to traffic could alter the risk of CHD mortality.Methods: We used a population-based cohort study with a 5-year exposure period and a 4-year follow-up period to explore the association between changes in residential proximity to road traffic and the risk of CHD mortality. The cohort comprised all residents aged 45-85 years who resided in metropolitan Vancouver during the exposure period and without known CHD at baseline (n = 450,283). Residential proximity to traffic was estimated using a geographic information system. CHD deaths during the follow-up period were identified using provincial death registration database. The data were analyzed using logistic regression.Results: Compared with the subjects consistently living away from road traffic (>150 m from a highway or >50 m from a major road) during the 9-year study period, those consistently living close to traffic (