HIGH-FIELD MAGNETIC ORIENTATION OF RED-BLOOD-CELLS

HIGH-FIELD MAGNETIC ORIENTATION OF RED-BLOOD-CELLS
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DOI:
10.1016/0921-4526(94)91170-3
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发表时间:
1994-07-01
期刊:
影响因子:
2.8
通讯作者:
DATE, M
DATE, M
中科院分区:
物理与天体物理3区
文献类型:
--
作者:
TAKEUCHI, T;MIZUNO, T;DATE, M

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在高达8T的静态强磁场中,研究了生物系统的磁取向。 正常红细胞(RBC)的取向使其圆盘平面平行于磁场,并在6T磁场周围获得完全取向。 这种取向不依赖于血红蛋白的自旋状态。 然而,凝固的红细胞,其中血红蛋白分子被凝固,被定向成其盘平面垂直于场方向。 凝固RBC的各向异性磁化率DELTA(chi)取决于血红蛋白的自旋状态。 这意味着凝固的红细胞的相反取向主要是由于血红蛋白的抗磁性和顺磁性各向异性。
Magnetic orientation of biological systems has been investigated in static high magnetic field up to 8 T. Normal red blood cells (RBCs) are oriented with their disk plane parallel to the field and full orientation is obtained around the field of 6 T. This orientation does not depend on the spin state of hemoglobins. However, solidified RBCs, in which hemoglobin molecules are solidified, are oriented with their disk plane perpendicular to the field direction. The anisotropic susceptibility DELTA(chi) of solidified RBCs depends on the spin state of hemoglobins. This means that the opposite orientation of solidified RBCs is mainly due to diamagnetic and paramagnetic anisotropy of hemoglobins.