Effect of airway surface liquid composition on laryngeal muscle activation.
Effect of airway surface liquid composition on laryngeal muscle activation.
复制标题
气道表面液体成分对喉肌激活的影响。
DOI：
10.1093/sleep/19.suppl_10.180
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发表时间：
1996
期刊：
影响因子：
5.6
通讯作者：
Sant'Ambrogio,G
中科院分区：
文献类型：
--
作者：
Kuna,ST;Sant'Ambrogio,FB;Sant'Ambrogio,G
研究了8只麻醉犬离体喉部雾化蒸馏水和异戊糖对喉部肌肉活动的影响。水气溶胶与后环杓活性峰值的增加有关，但对类甲状腺活性没有改变。生理盐水或异摩尔葡萄糖气雾剂对两种肌肉的活动都没有任何影响。当蒸馏水雾化后重复负压刺激时，喉负压引起的环杓后侧活动反射增强。结果表明，喉表面液体成分的改变改变了压力反应性喉受体的反应，从而改变了气道通畅维持肌的反射激活。
The effects of aerosolized distilled water and isosmolal dextrose in the isolated larynx on laryngeal muscle activity were studied in eight anesthetized dogs. Water aerosol was associated with an increase in peak posterior cricoarytenoid activity but no change in thyroarytenoid activity. Saline or isosmolal dextrose aerosols did not have any effect on the activity of either muscle. The reflex increase in posterior cricoarytenoid activity due to laryngeal negative pressure was enhanced when the negative pressure challenge was repeated following distilled water aerosol. The results suggest that alteration in laryngeal surface liquid composition modifies the response of pressure-responsive laryngeal receptors and, thereby, the reflex activation of airway patency maintaining muscles.