Forgetfulness: A role in noncompliance with antidepressant treatment
Forgetfulness: A role in noncompliance with antidepressant treatment
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DOI：
10.1177/070674370605101110
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发表时间：
2006-10-01
影响因子：
4
通讯作者：
Patten, Scott B.
中科院分区：
文献类型：
--
作者：
Bulloch, Andrew G.;Adair, Carol E.;Patten, Scott B.
目的：确定阿尔伯塔省人群抗抑郁治疗的不依从性程度，并调查不依从性的原因。方法：我们使用来自艾伯塔省心理健康调查（2003年进行的一项电话调查）的数据（n = 5323名成年人），对不遵守规定的频率和报告的不遵守规定的原因进行基于人群的估计。结果：在服用1、2或3种抗抑郁药物的受访者中，报告的不依从性为41.7%（95%置信区间[Cl]， 36.9%至46.6%）。服用1种抗抑郁药物的不依从性为42.0% (95%CI, 36.9% ~ 47.2%)，而服用2种或3种抗抑郁药物的不依从性为39.4% （95%CI, 26.7% ~ 53.6%）。在目前至少服用一种抗抑郁药的受访者中，64.9% （95%CI， 57.4%至71.7%）报告说，健忘是不遵守规定的最常见原因。服用1种药物的受访者中，64.1% （95%CI, 56.0% ~ 71.4%）报告健忘，服用2或3种药物的受访者中有71.3% （95%CI, 48.3% ~ 86.8%）报告健忘。不遵守的频率和报告的不遵守的原因与性别和年龄无关。结论：我们的研究重复了先前的报告，表明抗抑郁药物治疗的不依从性是常见的。忘记服药是最重要的不遵守报告的原因。
Objectives: To determine the degree of noncompliance with antidepressant treatment in the Alberta population and to investigate the reasons for noncompliance.Method: We used data from the Alberta Mental Health Survey, a telephone survey conducted in 2003 (n = 5323 adults), to produce population-based estimates of the frequency of noncompliance and the reported reasons for noncompliance.Results: Reported noncompliance was 41.7% (95% confidence interval [Cl], 36.9% to 46.6%) for respondents taking 1, 2, or 3 antidepressants. Noncompliance for those taking I antidepressant was 42.0% (95%CI, 36.9% to 47.2%), whereas noncompliance for those taking 2 or 3 antidepressants was 39.4% (95%CI, 26.7% to 53.6%). Among respondents currently taking at least one antidepressant, 64.9% (95%CI, 57.4% to 71.7%) reported that forgetfulness was the most common reason for noncompliance. Of respondents taking I medication, 64.1% (95%CI, 56.0% to 71.4%) reported forgetfulness as did 71.3% (95%CI, 48.3% to 86.8%) of those taking 2 or 3 medications. Both the frequency of noncompliance and the reported reasons for noncompliance were independent of sex and age.Conclusion: Our study replicates prior reports that indicate that noncompliance is common with antidepressant treatment. Forgetting to take medication is the most important reported reason for this noncompliance.