Rapidly increasing rates of hip fracture in Beijing, China
Rapidly increasing rates of hip fracture in Beijing, China
复制标题
中国北京髋部骨折发病率迅速上升
DOI：
10.1002/jbmr.519
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发表时间：
2012-01-01
影响因子：
6.2
通讯作者：
Cummings, Steven R.
中科院分区：
文献类型：
--
作者：
Xia, Wei-Bo;He, Shu-Li;Cummings, Steven R.
在西方大多数国家，髋部骨折的年龄特异性发病率一直在下降，但一些研究表明，在亚洲正在经历城市化的地区，髋部骨折的发病率可能会上升。我们曾于1990年至1992年在中国北京进行了一项基于人群的髋部骨折率研究，其中包括髋部骨折病例的验证。使用类似的方法来验证的情况下，我们估计了年龄特定的髋部骨折率在北京，中国，2002年至2006年。具体而言，我们获得了向北京市公共卫生局报告的髋部骨折的出院数据。为了确认诊断，北京居住，并找到公共记录中遗漏的病例，我们在北京医院随机抽样的医疗记录中检查了公共卫生记录中的个别病例。公共卫生数据中的发病率根据这些低估和高估进行了调整。我们发现，在1990年至1992年以及2002年至2006年期间，50岁以上髋部骨折的校正年龄特异性比率在女性中增加了2.76倍（95%置信区间[CI]，2.682.84），在男性中增加了1.61倍（95% CI，1.561.66）。超过70岁，女性的年龄特异性比率增加3.37倍（95%CI，3.283.47），男性增加2.01倍（95%CI，1.952.07）。从2002年到2006年，50岁以上的妇女和男子的死亡率分别增加了58%和49%。我们的结论是髋部骨折的比率在中国北京一直在迅速上升。因此，髋部骨折的负担可能会迅速从西部转移到东部的城市化地区。(C)2012年美国骨与矿物质研究学会
The age-specific rates of hip fractures have been declining in most countries in the West but a few studies suggest that the rates might be increasing in areas of Asia that are undergoing urbanization. We previously conducted a population-based study of hip fracture rates in Beijing, China, in 1990 to 1992 that included validation of hip fracture cases. Using a similar approach to validate cases, we estimated the age-specific hip fracture rates in Beijing, China, for 2002 to 2006. Specifically, we obtained hospital discharge data for hip fractures that were reported to the Beijing Bureau of Public Health. To confirm the diagnoses, Beijing residence, and find cases missed by the public records we checked individual cases in the public health records against medical records in a random sample of Beijing hospitals. The rates from public health data were adjusted for these under- and overestimations. We found that between 1990 and 1992 and 2002 and 2006, the adjusted age-specific rates of hip fracture over age 50 years increased 2.76-fold (95% confidence interval [CI], 2.682.84) in women and 1.61-fold (95% CI, 1.561.66) in men. Over age 70 years, the age-specific rates increased 3.37-fold (95% CI, 3.283.47) in women and 2.01-fold (95% CI, 1.952.07) in men. From 2002 to 2006, the rates over age 50 years increased 58% in women and 49% in men. We conclude that the rate of hip fracture has been rising very rapidly in Beijing, China. Therefore, the burden of hip fractures may be shifting rapidly from the West to urbanizing areas of the East. (C) 2012 American Society for Bone and Mineral Research